Mal-Acetyl-Beta-Ala-Val-Cit-PAB(m-PEG8)-PNP Size:25mg also referred to as the

also referred to as the Cu(I)-catalyzed free click reaction

38 SMILES Cl

Product Name Lenalidomide-CO-PEG6-C2-Cl Synonyms Lenalidomide-4'-CO-PEG6-C2-Cl CAS Number n/a Related CAS Molecular Formula C28H40ClN3O10 Molecular Weight 614

Development of PDE6D and CK1a Degraders through Chemical Derivatization of FPFT-2216

483 Purity (HPLC) >= 95% Solubility DMSO

Mal-Acetyl-Beta-Ala-Val-Cit-PAB(m-PEG8)-PNP Size:25mg also referred to as theSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The PNP (para nitrophenyl) moiety serves as an activating leaving group, enabling efficient and selective conjugation of the payload to the linker. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as